张伟

男,博士,研究员。

 

2000年毕业于北京大学医学部临床医学七年制。2004年就读于香港科技大学生物化学系,从事神经信号传导通路及分子机制方面的研究,2008年获得生物化学博士学位。2011年入职深圳北京大学香港科技大学医学中心,长期从事免疫过敏性疾病及肿瘤发生发展机制等方面的基础研究。在EMBO Reports、Molecular & Cellular Biology、Arthritis & Rheumatology、the Journal of Cell Biology等杂志共发表SCI论文74篇(其中通讯作者27篇、共同通讯作者21篇、第一作者2篇、共同第一作者4篇)。

 

代表性论文:

1.   Zhou Y, Pan DS, Shan S, Zhu JZ, Zhang K, Yue XP, Nie LP, Wan J, Lu XP, Zhang W, Ning ZQ. Non-toxic dose chidamide synergistically enhances platinum-induced DNA damage responses and apoptosis in Non-Small-Cell lung cancer cells. Biomed Pharmacother. 2014; 68(4):483-91.

2.   Nie G, Duan H, Li X, Yu Z, Luo L, Lu R, Ji Z, Zhang W. MiR-205 promotes the tumorigenesis of nasopharyngeal carcinoma through targeting TP53INP1. Molecular Medicine Reports. 2015; 12(4): 5715-22.

3.   Li F, Qu H, Cao HC, Li MH, Chen C, Chen XF, Yu B, Yu L, Zheng LM, Zhang W. Both FOXO3a and FOXO1 are involved in the HGF-protective pathway against apoptosis in Endothelial Cells. Cell Biology International. 2015; 39(10): 1131-7.

4.   Ye T, Chen B, Yu B, Zhong Q, Huang G, Hu X, Zhang W. Susceptibility of Ureaplasma urealyticum to Methylene Blue-Mediated Photodynamic Antimicrobial Chemotherapy: An in vitro Study. Photochem Photobiol. 2015; 91(4): 917-22. doi: 10.1111/php.12438.

5.   Yu Y, Zhang Y, Zhang J, Dou X, Yang H, Shao Y, Wang K, Yu B, Zhang W, Lau HY. Impaired Toll-like receptor 2-mediated Th1 and Th17/22 cytokines secretion in human peripheral blood mononuclear cells from patients with atopic dermatitis. J Transl Med. 2015; 13: 384. doi: 10.1186/s12967-015-0744-1.

6.   Zhang YY, Yu YY, Zhang YR, Zhang W, Yu B. The Modulatory Effect of TLR2 on LL-37-induced Human Mast Cells Activation. Biochem Biophys Res Commun. 2016; 470(2): 368-74.

7.   Fan CY, Wu Q, Ye XY, Luo HX, Yan DD, Xiong Y, Zhu HL, Diao YR, Zhang W, Wan J. Role of miR-211 in neuronal differentiation and viability: implications to pathogenesis of Alzheimer’s disease. Frontiers in Aging Neuroscience. 2016; 8: 166.

8.   Yang YT, Wang YF, Lai JY, Shen SY, Wang F, Kong J, Zhang W, Yang HY. Long non-coding RNA UCA1 contributes to the progression of oral squamous cell carcinoma via regulating WNT/β-catenin signaling pathway. Cancer Sci. 2016; 107(11): 1581-1589.

9.   Wu Q, Ye X, Xiong Y, Zhu H, Miao J, Zhang W, Wan J. The protective role of microRNA-200c in Alzheimer’s disease pathologies is induced by beta Amyloid-triggered Endoplasmic Reticulum Stress. Front Mol Neurosci. 2016; 9: 140. doi: 10.3389/fnmol.2016.00140.

10.  Liu S, Zhang Q, Huang D, Zhang W, Zhong F, Feng J, Chen X, Meng Q, Chen X, Zhang W, Zhang H.Comprehensive assessment of peripheral blood TCRβ repertoire in infectious mononucleosis and chronic active EBV infection patients. Annals of Hematology. 2017; 96(4): 665-680.

11.  Chen XF, Zhang LJ, Zhang J, Dou X, Shao Y, Jia XJ, Zhang W, Yu B. MiR-151a is involved in the pathogenesis of atopic dermatitis by regulating interleukin-12 receptor β2. Exp Dermatol. 2018; 27(4): 427-432. doi: 10.1111/exd.13276. 

12.  Chen X, Wan J, Yu B, Diao Y, Zhang W. PIP5K1α promotes myogenic differentiation via AKT activation and calcium release. Stem Cell Res Ther. 2018; 9(1): 33. doi: 10.1186/s13287-018-0770-z.


本网站由阿里云提供云计算及安全服务